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Engineered Cells

Knockout Immortalized Cell Lines

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Streamline your gene editing with tailored CRISPR knockout pools and clones. Assay-ready cells using our advanced XDel design for high performance, or single-guide design. No optimization needed. Choose your target and cell line, and we'll take care of the rest.
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Data

XDel Knockout Cells Enable High and Sustained Protein Depletion - Guaranteed and Delivered in 4 Weeks (Pools) or 10 Weeks (Clones)
XDel Knockout Cells Enable High and Sustained Protein Depletion - Guaranteed and Delivered in 4 Weeks (Pools) or 10 Weeks (Clones)
Figure 1. A) Four membrane proteins were knocked out in K562 cells using XDel technology, following EditCo Bio’s proprietary workflow. Protein levels were assessed via flow cytometry at four time points: days 3, 7, 14, and 21 post-transfection, and compared to negative controls (non-edited cells or cells electroporated with Cas9 only). Membrane protein depletion remained stable over time, and cell viability was consistently high (>90%) across all samples. B) Representative flow cytometry plots showing protein levels for CD46 and CD59 in XDel knockout pools at 21 days post-editing.
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About XDel Technology

XDel is a cutting-edge CRISPR knockout technology designed to remove the guesswork from gene editing. By leveraging an innovative guide RNA design strategy, XDel delivers highly efficient, consistent, and reproducible gene knockouts—empowering researchers to accelerate their discoveries with confidence.